Acta mathematica scientia, Series B >
QUALITATIVE ANALYSIS OF HEPATITIS B VIRUS INFECTION MODEL WITH IMPULSIVE VACCINATION AND TIME DELAY
Received date: 2009-02-23
Revised date: 2009-12-07
Online published: 2011-05-20
Supported by
This work was supported by the Fundamental Research Funds for the Central Universities, China University of Geosciences (Wuhan) CUGL100238 and 2011CB710600 (973 Program).
According to the epidemic state, propagation mode and transformation between HBV infection states, the Hepatitis B Virus (HBV) infection with impulsive vaccination and time delay are modelled and analyzed. The control methods of impulsive vaccination and active therapy are adopted. By using comparative theorem of impulsive differential equation, the sufficient conditions that Hepatitis B Virus will be eliminated eventually or be persistent are derived.
QIAO Mei-Hong , QI Huan , CHEN Ying-Chun . QUALITATIVE ANALYSIS OF HEPATITIS B VIRUS INFECTION MODEL WITH IMPULSIVE VACCINATION AND TIME DELAY[J]. Acta mathematica scientia, Series B, 2011 , 31(3) : 1020 -1034 . DOI: 10.1016/S0252-9602(11)60294-4
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